Regulatory T cells are important for ensuring that the immune system does not attack self and does not overreact to external antigens. Understanding how these cells develop and maintain stable function provides general insights into cellular differentiation in general, as well as new opportunities for therapeutic manipulation.
Herman Waldmann, Stephen Cobbold. Regulatory T Cells: Context Matters Immunity – 22 May 2009 (Vol. 30, Issue 5, pp. 613-615 View Full Paper