In a new study researchers from Clemson University found various grape extracts and their compounds to be effective at inhibiting Helicobacter pylori, one of the leading causes of gastritis in humans. The antibacterial effects of extracts from red, white, black and muscadine grapes as well as the pure compounds resveratrol, ellagic acid, and myricetin were tested for anti-H. pylori activity using agar dilution, laser scanning microscopy and cell proliferation. Following 24 hour treatment, results showed that muscadine grape skin extract had the highest anti-H. pylori effect, followed by muscadine grape synergy and seed extract. Additionally, two of the three compounds, resveratrol and ellagic acid, also inhibited H. pylori.
Brown et al. Antibacterial Effects of Grape Extracts on Helicobacter pylori. Applied and Environmental Microbiology, 2008; 75 (3): 848 View Abstract